A secure delivery system according to various aspects of the present technology comprises a transport box having a storage space, an environmental control unit, a plurality of electrical contacts, and a deployable receiving tray responsive to automated delivery systems. The transport box fits within an interior space of a delivery box having a GPS receiver that provides a geographic delivery location of the delivery box. The delivery box comprises a plurality of corresponding electrical contacts configured to be coupled to the electrical contacts of the transport box to provide power to the transport box. The delivery box may further comprise an electronic lock that is responsive to a delivery box controller circuit configured to operate the electronic lock.