A synthetic skin patch for a medical needle insertion training device. The training device has a training region, at least one synthetic vein in the training region, and a plurality of fastening structures positioned about the training region. The skin patch comprises an elastic, substantially flat central body, and a plurality of connectors positioned about the perimeter of the central body. The connectors positionally match and mate with the fastening structures on the training device to secure the skin patch to the training device over the training region.