A display substrate, a driving method therefor, and a display device are provided. The display substrate includes: a base substrate, provided with multiple pixel islands discretely provided, the pixel islands including multiple subpixels distributed in an array; a plurality of pixel circuits, arranged in the subpixels respectively, each of the pixel circuits including a driving transistor and a light-emitting component, a first electrode of the driving transistor being electrically connected to a first power supply end, a second electrode of the driving transistor being electrically connected to an anode of the light-emitting component, and a cathode of the light-emitting component being electrically connected to a second power supply end; and multiple light emission control circuits, each arranged at a gap between adjacent pixel islands, the light emission control circuit being electrically connected between the first power supply end and the first electrode of the driving transistor.