A method and device for timing in time-varying distance protection based on multiple lines of a tower. The method includes: collecting an instantaneous current value at a time-varying distance protection installation location in the multiple lines of the tower, and acquiring preset parameters; calculating, according to the preset parameters and a multi-line ranging model, a multi-line ranging result; calculating, according to the preset parameters, the multi-line ranging result, and an adaptive calculation model, time of a section-II distance protection action and final time of a section-III distance protection action; and determining, according to the instantaneous current value, the preset parameters, and a cross-line failure auxiliary criterion model, final time of the section-II distance protection action.