Invention Grant
- Patent Title: Cereblon binders for the degradation of ikaros
-
Application No.: US17031550Application Date: 2020-09-24
-
Publication No.: US11753397B2Publication Date: 2023-09-12
- Inventor: James A. Henderson , Gesine Kerstin Veits , Minsheng He , Christopher G. Nasveschuk , Andrew J. Phillips , Andrew Charles Good
- Applicant: C4 Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: C4 Therapeutics, Inc.
- Current Assignee: C4 Therapeutics, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Knowles Intellectual Property Strategies, LLC
- Main IPC: C07D401/14
- IPC: C07D401/14
Abstract:
The invention provides cereblon binders of Formulas:
or pharmaceutically acceptable salts thereof, for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway along with their use in therapeutic applications to treat medical disorders including, but not limited to cancer.
or pharmaceutically acceptable salts thereof, for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway along with their use in therapeutic applications to treat medical disorders including, but not limited to cancer.
Public/Granted literature
- US20210009559A1 CEREBLON BINDERS FOR THE DEGRADATION OF IKAROS Public/Granted day:2021-01-14
Information query
