Invention Grant
- Patent Title: Methods for using mosaicism in nucleic acids sampled distal to their origin
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Application No.: US17065406Application Date: 2020-10-07
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Publication No.: US11753686B2Publication Date: 2023-09-12
- Inventor: John West
- Applicant: Personalis, Inc.
- Applicant Address: US CA Menlo Park
- Assignee: Personalis, Inc.
- Current Assignee: Personalis, Inc.
- Current Assignee Address: US CA Menlo Park
- Agency: Orrick, Herrington & Sutcliffe, LLP
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886 ; A61K31/7068 ; G16B45/00 ; C12Q1/6809 ; C12Q1/6827
Abstract:
Disclosed herein are methods for improving detection and monitoring of human diseases. The methods can be used to provide spatial and/or developmental localization of the source of each differential mutation within the body. The methods can also be used to generate a mutation map of a subject. And the mutation map can be used to monitoring state(s) of health of one or more tissues of a subject.
Public/Granted literature
- US20210062276A1 METHODS FOR USING MOSAICISM IN NUCLEIC ACIDS SAMPLED DISTAL TO THEIR ORIGIN Public/Granted day:2021-03-04
Information query
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