A portable, battery-operated vacuum infusion machine includes a top container assembly with a compartment that houses an air pump, a battery, and a controller. The top container assembly couples to the top opening of a separate bottom container. When coupled together, the top and bottom containers are connected by flow holes superimposed by a filter in the top container. An air pump switched on or off by a controller exerts negative pressure in the bottom container by means of a suction port and induces liquid in the top container to enter the bottom container under pressure while the filter in the top container ensures that the infusion residue is separated from the liquid and only the prepared infusion has passage to the bottom container. The bottom container can be opened by means of removing the top container in order to allow for serving the prepared infusion.