A portable disinfecting apparatus with effective disinfection properties against pathogens, such as bacteria, fungi, and viruses is disclosed. Embodiments of the portable disinfecting apparatus include a portable sterilization box having at least one path configured to receive drawn air and to irradiate the drawn air with UV radiation along the path to produce disinfected air. The path may be provided using baffles that are configured, for example, in a serpentine or spiral configuration to provide a non-linear flow path for the air. The UV light sources, such as UV LEDs may be mounted on the baffles. Embodiments of the apparatus include an intake tube connected to the sterilization box for drawing air into the sterilization box from a point high within the room that is to be disinfected. The disinfected air is released from the sterilization box a point lower in the room. As the air is slightly heated during the disinfection process, drawing in air from high in the room and releasing the disinfected air lower in the room provides circulation and mixing of the disinfected air.