Invention Grant
- Patent Title: Process for the preparation of high purity Levosimendan
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Application No.: US17572331Application Date: 2022-01-10
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Publication No.: US11760730B2Publication Date: 2023-09-19
- Inventor: Chiragkumar Anilkumar Bhatt , Keyurkumar Amrutla Pandya , Pankaj Vasudev Parmar , John Muthiah Raja Jeyakumar
- Applicant: Navinta, LLC
- Applicant Address: US NJ Ewing
- Assignee: Navinta, LLC
- Current Assignee: Navinta, LLC
- Current Assignee Address: US NJ Ewing
- Agency: ST. ONGE STEWARD JOHNSTON & REENS LLC
- Main IPC: C07D237/14
- IPC: C07D237/14
Abstract:
An improved process for the preparation of high purity Levosimendan includes treatment of Levosimendan crude with an organic acid, adding an organic acid to precipitate Levosimendan and isolating pure Levosimendan from the precipitate. Levosimendan obtained by the improved process is pharmaceutically acceptable with no impurity higher than 0.2 percent.
Public/Granted literature
- US20220220080A1 PROCESS FOR THE PREPARATION OF HIGH PURITY LEVOSIMENDAN Public/Granted day:2022-07-14
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