Invention Grant
- Patent Title: Mitragynine analogs for the treatment of pain, mood disorders and substance use disorders
-
Application No.: US17177051Application Date: 2021-02-16
-
Publication No.: US11760758B2Publication Date: 2023-09-19
- Inventor: Andrew C. Kruegel , Dalibor Sames , Srijita Bhowmik , Vaclav Havel , Juraj Galeta , Jonathan A. Javitch , Susruta Majumdar
- Applicant: The Trustees of Columbia University in the City of New York , The Research Foundation for Mental Hygiene, Inc. , Sloan-Kettering Institute for Cancer Research
- Applicant Address: US NY New York
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,THE RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC.,SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,THE RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC.,SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
- Current Assignee Address: US NY New York; US NY Menands; US NY New York
- Agent Gary J. Gershik
- Main IPC: C07D471/14
- IPC: C07D471/14 ; A61K31/4375 ; C07D471/20 ; C07D491/22

Abstract:
The present invention provides a compound having the structure:
or a pharmaceutically acceptable salt or ester thereof, and a method of treating a subject afflicted with pain, a depressive disorder, a mood disorder or an anxiety disorder by administering the compound to the subject.
or a pharmaceutically acceptable salt or ester thereof, and a method of treating a subject afflicted with pain, a depressive disorder, a mood disorder or an anxiety disorder by administering the compound to the subject.
Public/Granted literature
- US20210179619A1 MITRAGYNINE ANALOGS FOR THE TREATMENT OF PAIN, MOOD DISORDERS AND SUBSTANCE USE DISORDERS Public/Granted day:2021-06-17
Information query