Invention Grant
- Patent Title: Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
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Application No.: US17243455Application Date: 2021-04-28
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Publication No.: US11760794B2Publication Date: 2023-09-19
- Inventor: Robert Seder , Neville Kisalu , Azza Idris , Barbara Flynn , Stephen Hoffman
- Applicant: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES , Sanaria Inc.
- Applicant Address: US MD Bethesda
- Assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services,Sanaria Inc.
- Current Assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services,Sanaria Inc.
- Current Assignee Address: US MD Bethesda; US MD Rockville
- Agency: Klarquist Sparkman LLP
- Main IPC: C07K16/20
- IPC: C07K16/20

Abstract:
Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection.
Public/Granted literature
- US20210253683A1 NEUTRALIZING ANTIBODIES TO PLASMODIUM FALCIPARUM CIRCUMSPOROZOITE PROTEIN AND THEIR USE Public/Granted day:2021-08-19
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