Invention Grant
- Patent Title: Compositions and methods for organoid generation and disease modeling
-
Application No.: US16301671Application Date: 2017-05-24
-
Publication No.: US11760977B2Publication Date: 2023-09-19
- Inventor: Ronald Evans , Michael Downes , Annette Atkins , Eiji Yoshihara , Ruth Yu
- Applicant: SALK INSTITUTE FOR BIOLOGICAL STUDIES
- Applicant Address: US CA La Jolla
- Assignee: SALK INSTITUTE FOR BIOLOGICAL STUDIES
- Current Assignee: SALK INSTITUTE FOR BIOLOGICAL STUDIES
- Current Assignee Address: US CA La Jolla
- Agency: Greenberg Traurig, LLP
- Agent Melissa Hunter-Ensor; Leslie Serunion
- International Application: PCT/US2017/034278 2017.05.24
- International Announcement: WO2017/205511A 2017.11.30
- Date entered country: 2018-11-14
- Main IPC: C12N5/071
- IPC: C12N5/071 ; G01N33/50 ; A61K35/39

Abstract:
The invention features pancreatic islet and pancreatic organoids, and cell cultures and methods that are useful for the rapid and reliable generation of pancreatic islet and pancreatic islet organoids. The invention also features methods of treating pancreatic diseases and methods of identifying agents that are useful for treatment of pancreatic diseases, such as type 2 diabetes and pancreatic cancer, using the pancreatic islet and pancreatic organoids of the invention.
Public/Granted literature
- US20190211310A1 COMPOSITIONS AND METHODS FOR ORGANOID GENERATION AND DISEASE MODELING Public/Granted day:2019-07-11
Information query