Invention Grant
- Patent Title: Splice variants associated with neomorphic SF3B1 mutants
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Application No.: US17098940Application Date: 2020-11-16
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Publication No.: US11761045B2Publication Date: 2023-09-19
- Inventor: Lihua Yu , Kian Huat Lim , Jacob D. Feala , Silvia Buonamici , Yoshiharu Mizui , Peter G. Smith , Ping Zhu , Eunice Sun Park , Michael W. Seiler , Marco Peter Fekkes
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886 ; A61P35/00 ; A61K31/4545 ; A61K31/495 ; A61K31/55 ; C12Q1/02 ; C12Q1/6806 ; C12Q1/6841
Abstract:
Splice variants associated with neomorphic SF3B1 mutations are described herein. This application also relates to methods of detecting the described splice variants, and uses for diagnosing cancer, evaluating modulators of SF3B1, and methods of treating cancer associated with mutations in SF3B1.
Public/Granted literature
- US20210130909A1 SPLICE VARIANTS ASSOCIATED WITH NEOMORPHIC SF3B1 MUTANTS Public/Granted day:2021-05-06
Information query
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