An endoscope eyepiece grasping mechanism includes a base part engaging a tab member via a connected engagement member. An annular part has an outer engagement surface and an inner camming surface disposed coaxially with the base part and axially moveable relative to the base part. The engagement surface is moveable with the camming surface to move the tab member radially outwardly, with a movement of the annular part relative to the base part in a first axial direction, toward a receiving position, and to move the tab member radially inwardly, with movement of the annular part relative to the base part in a second axial direction, toward a grasping position. A biasing device acts to bias the annular part toward the grasping position. An endoscope eyepiece is engaged by the tab member upon the annular part moving from the receiving position to the grasping position.