Invention Grant
- Patent Title: Biodegradable contraceptive implants
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Application No.: US16344663Application Date: 2017-10-24
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Publication No.: US11766400B2Publication Date: 2023-09-26
- Inventor: W. Mark Saltzman , Elias Quijano , Fan Yang , Zhaozhong Jiang , Derek Owen
- Applicant: Yale University , Family Health International
- Applicant Address: US CT New Haven
- Assignee: YALE UNIVERSITY,FAMILY HEALTH INTERNATIONAL
- Current Assignee: YALE UNIVERSITY,FAMILY HEALTH INTERNATIONAL
- Current Assignee Address: US CT New Haven; US NC Durham
- Agency: PABST PATENT GROUP LLP
- International Application: PCT/US2017/058107 2017.10.24
- International Announcement: WO2018/081138A 2018.05.03
- Date entered country: 2019-04-24
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K31/567

Abstract:
Biodegradable contraceptive implants and methods of making and using thereof, are preferably formed of poly(ω-pentadecalactone-co-p-dioxanone) [poly(PDL-co-DO)], a family of polyester copolymers that degrade slowly in the presence of water. The material is suitable as the basis of a biodegradable contraceptive implant that provides sustained release of a progestin at a rate similar to a commercially available nondegradable implant. In a preferred embodiment, the progestin is levonorgestrel (LNG), a hormone that prevents pregnancy by preventing the release of an egg from the ovary or by preventing fertilization of the egg by sperm. The implant may be inserted subcutaneously, allowing degradation over a period of up to about 18 or 24 months, eliminating the need for removal by a trained practitioner.
Public/Granted literature
- US20200054553A1 BIODEGRADABLE CONTRACEPTIVE IMPLANTS Public/Granted day:2020-02-20
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