Invention Grant
- Patent Title: Methods for production of MSC-derived exosomes
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Application No.: US16762439Application Date: 2018-11-16
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Publication No.: US11766402B2Publication Date: 2023-09-26
- Inventor: Elizabeth Shpall , Raghu Kalluri , Katy Rezvani , Mayela Mendt , Valerie Lebleu , Sushrut Kamerkar
- Applicant: Board of Regents, The University of Texas System
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Norton Rose Fulbright US LLP
- International Application: PCT/US2018/061657 2018.11.16
- International Announcement: WO2019/099927A 2019.05.23
- Date entered country: 2020-05-07
- Main IPC: A61K35/28
- IPC: A61K35/28 ; C12N15/113 ; A61K9/127 ; A61K9/00 ; A61K31/7105 ; A61K31/713 ; A61K45/06 ; C12N5/0775 ; C12Q1/68
Abstract:
Provided herein are methods of manufacturing clinical grade exosomes derived from mesenchymal stem cells (MSCs). Further provided are methods of loading the exosomes with therapeutic agents, such as siRNA. Also provided herein are methods of treating diseases by administering the clinical grade exosomes.
Public/Granted literature
- US20210186877A1 METHODS FOR PRODUCTION OF MSC-DERIVED EXOSOMES Public/Granted day:2021-06-24
Information query
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