Invention Grant
- Patent Title: Peptide-targeted liposomal delivery for treatment, diagnosis, and imaging of diseases and disorders
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Application No.: US16825371Application Date: 2020-03-20
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Publication No.: US11766403B2Publication Date: 2023-09-26
- Inventor: Kamal D. Moudgil , Rakeshchandra R. Meka
- Applicant: University of Maryland, Baltimore , The United States Government as represented by the Department of Veterans Affairs
- Applicant Address: US MD Baltimore
- Assignee: University of Maryland, Baltimore,The United States Government as represented by the Department of Veterans Affairs
- Current Assignee: University of Maryland, Baltimore,The United States Government as represented by the Department of Veterans Affairs
- Current Assignee Address: US MD Baltimore; US DC Washington
- Agency: Riverside Law LLP
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61K38/08 ; A61K47/42 ; A61K47/64 ; A61K47/69 ; C07K7/06 ; A61P19/02
Abstract:
The present invention relates in part to compositions for targeted delivery of an agent and agent delivery systems comprising a novel tissue-targeting peptide ligand (CKPFDRALC) (SEQ ID NO: 1) named ART-2. In certain aspects, the ART-2-coated liposomes encapsulating an agent, such as a therapeutic agent, diagnostic agent, imaging agent, or any combination thereof, were more effective in inhibiting, diagnosing, or imaging a disease or disorder, such as an arthritis progression, than control, despite a comparable safety profile.
Public/Granted literature
- US20200297633A1 PEPTIDE-TARGETED LIPOSOMAL DELIVERY FOR TREATMENT, DIAGNOSIS, AND IMAGING OF DISEASES AND DISORDERS Public/Granted day:2020-09-24
Information query
