Invention Grant
- Patent Title: Pyrimidinone derivatives as CDC7 inhibitors
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Application No.: US17244171Application Date: 2021-04-29
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Publication No.: US11766434B2Publication Date: 2023-09-26
- Inventor: Emma L. Carswell , Mark David Charles , Chukuemeka Tennyson Ekwuru , Frederic Elustondo , Katherine M. Fowler , Gregory R. Ott , Jonathan R. Roffey , Joanna L. Brookfield , Daniel James Ford , Mathew L. Calder
- Applicant: Cancer Research Technology Limited
- Applicant Address: GB London
- Assignee: Cancer Research Technology Limited
- Current Assignee: Cancer Research Technology Limited
- Current Assignee Address: GB London
- Agency: Foley Hoag LLP
- Agent David P. Halstead; Benjamin A. Vaughan
- Priority: GB 18845 2016.11.08
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/437 ; A61K31/551 ; C07D403/14 ; C07D413/14 ; C07D417/14 ; C07D471/04
Abstract:
The present invention relates to compounds of formula I as defined herein, and salts and solvates thereof, that function as inhibitors of cell division cycle 7 (Cdc7) kinase enzyme activity. The present invention also relates to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which Cdc7 kinase activity is implicated.
Public/Granted literature
- US20220079942A1 PYRIMIDINONE DERIVATIVES AS CDC7 INHIBITORS Public/Granted day:2022-03-17
Information query
IPC分类:
