Invention Grant
- Patent Title: Genomic deletion in African swine fever vaccine allowing efficient growth in stable cell lines
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Application No.: US17130814Application Date: 2020-12-22
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Publication No.: US11766476B2Publication Date: 2023-09-26
- Inventor: Douglas P. Gladue , Manuel V. Borca
- Applicant: The United States of America, as represented by the Secretary of Agriculture
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by The Secretary of Agriculture
- Current Assignee: The United States of America, as represented by The Secretary of Agriculture
- Current Assignee Address: US DC Washington
- Agent John D. Fado; Mark D. McNemar
- Main IPC: C12N7/00
- IPC: C12N7/00 ; A61K39/12 ; C12N7/04 ; A61K39/00
Abstract:
Provided herein are details on the construction of a recombinant African Swine Fever Virus (ASFV) live attenuated vaccine for prevention of ASF caused by various strains of ASFV, such as the highly virulent Georgia 2007 isolate (“ASFV-G”). An exemplary vaccine comprises a deletion of multiple genes allowing for industrial-scale growth in stable cell lines.
Public/Granted literature
- US20220193217A1 GENOMIC DELETION IN AFRICAN SWINE FEVER VACCINE ALLOWING EFFICIENT GROWTH IN STABLE CELL LINES Public/Granted day:2022-06-23
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