The release film transfer printing equipment is provided. The release film transfer printing equipment includes a machine, a platform, a transfer device and a downward pressing device. The machine has a control panel. The platform is disposed above the machine, and the platform includes a vacuum pump electrically connected to the control panel. The transfer device includes a mold and a release film fixing frame. The mold is disposed above the platform, and the mold includes a plurality of air holes. The release film fixing frame is connected to a periphery of the platform. The downward pressing device is disposed above the transfer device, and the downward pressing device includes a hydraulic cylinder and a downward pressing platform. The hydraulic cylinder is electrically connected to the control panel, and the downward pressing platform is connected to the hydraulic cylinder by a power rod.