A system for controlling the climate of a cab of an autonomously operable machine when operated unmanned, and related machine. The system includes at least one temperature sensor to generate a signal indicative of the temperature within the cab and a controller configured to receive the signal as well as determine if the machine is being operated unmanned. If the machine is being operated unmanned, the controller is further configured to generate machine control commands to turn on the cab cooling device or cab heating device and adjust a blower as needed to maintain the cab temperature above the minimum and/or below the maximum temperature thresholds.