Invention Grant
- Patent Title: Benzimidamides compounds comprising an oxaborinin ring
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Application No.: US17738097Application Date: 2022-05-06
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Publication No.: US11767333B2Publication Date: 2023-09-26
- Inventor: John Liddle , Ann Louise Walker , Gemma Victoria White , Alexis Denis , Nerina Dodic , Marie-Hélène Fouchet , Anne Bouillot
- Applicant: INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM)
- Applicant Address: FR Paris
- Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
- Current Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
- Current Assignee Address: FR Paris
- Agency: Sheppard Mullin Richter & Hampton LLP
- Priority: GB 09378 2018.06.07
- Main IPC: C07F5/02
- IPC: C07F5/02
Abstract:
The invention relates to 4-(1-hydroxy-3,4-dihydro-1H-benzo[c][1,2]oxaborinin-3-yl)benzimidamide derivatives and their use in treating diseases and conditions of the skin (for example, Netherton syndrome, rosacea, atopic dermatitis, psoriasis and itch) caused by abnormally high levels of protease activity (particularly of serine proteases such as kallikreins). In addition, the invention relates to compositions containing the derivatives and processes for their preparation.
Public/Granted literature
- US20220267357A1 Novel Benzimidamides Compounds Comprising an Oxaborinin Ring Public/Granted day:2022-08-25
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