Invention Grant
- Patent Title: Antibody-coupled cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors
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Application No.: US17168503Application Date: 2021-02-05
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Publication No.: US11767354B2Publication Date: 2023-09-26
- Inventor: Mark Macielag , Raymond J. Patch , Rui Zhang , Martin A. Case , Shamina M. Rangwala , James N. Leonard , Raul C. Camacho , Michael J. Hunter , Katharine E. D'Aquino , Wilson Edwards , Ronald V. Swanson , Wenying Jian , Yue-Mei Zhang , Mark J. Wall , Ellen Chi
- Applicant: Janssen Pharmaceutica NV
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agency: Seed IP Law Group LLP
- Main IPC: C07K14/575
- IPC: C07K14/575 ; A61K47/68 ; C07K16/24 ; A61K9/00 ; A61K38/17 ; A61K38/26 ; C07K1/06 ; C07K1/107 ; A61K47/64 ; A61P3/10 ; A61K49/00 ; C07K1/12 ; C07K1/18 ; C07K5/02 ; A61K47/60 ; A61P3/08 ; A61P3/00 ; A61P3/04 ; A61P3/06 ; A61K38/22 ; A61K45/06 ; C07K16/00 ; A61K38/00 ; A61K39/00

Abstract:
The present invention comprises conjugates comprising a monoclonal antibody conjugated to a cyclic PYY peptide. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel conjugates are useful for preventing, treating or ameliorating diseases and disorders disclosed herein.
Public/Granted literature
- US20210163566A1 Antibody-Coupled Cyclic Peptide Tyrosine Tyrosine Compounds as Modulators of Neuropeptide Y Receptors Public/Granted day:2021-06-03
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