Invention Grant
- Patent Title: Glycyrrhetinic acid derivatives for treating hyperkalemia
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Application No.: US16636596Application Date: 2018-08-06
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Publication No.: US11768319B2Publication Date: 2023-09-26
- Inventor: Gary Luehr , Dean Dragoli , Michael Leadbetter , Tao Chen , Jason Lewis
- Applicant: Ardelyx, Inc.
- Applicant Address: US CA Fremont
- Assignee: Ardelyx, Inc.
- Current Assignee: Ardelyx, Inc.
- Current Assignee Address: US CA Fremont
- Agency: Viksnins Harris Padys Malen LLP
- International Application: PCT/US2018/045421 2018.08.06
- International Announcement: WO2019/060051A 2019.03.28
- Date entered country: 2020-02-04
- Main IPC: C07J63/00
- IPC: C07J63/00 ; A61P5/44 ; G02B5/02 ; G02B5/20 ; G02B3/00 ; G02F1/1335 ; G02B27/00
Abstract:
The present invention provides a compound of formula (I) or a salt thereof: (I) wherein X, L, V, R1, R2, R3 and R4, are as defined herein. These compounds are inhibitors of 11-hydroxysteroid dehydrogenase type 2 (11-HSD-2) and are used to treat hyperkalemia.
Public/Granted literature
- US20210163524A1 GLYCYRRHETINIC ACID DERIVATIVES FOR TREATING HYPERKALEMIA Public/Granted day:2021-06-03
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