The present invention discloses a communication apparatus having feedback calibration mechanism. A signal transmission circuit generates a RF analog signal according to a digital signal. A signal amplifying circuit amplifies the RF analog signal to generate an amplified analog signal. A LC impedance matching circuit transmits the amplified analog signal to the antenna to perform transmission. A feedback calibration circuit includes a feedback inductive circuit and a calibration circuit. A feedback inductive circuit is inductively coupled to the LC impedance matching circuit to receive the amplified analog signal to generate a feedback signal. A calibration circuit determines a distorted amount of the feedback signal relative to the RF analog signal to modify an operation parameter of at least one of the signal transmission circuit and the signal amplifying circuit to decrease the distorted amount.