Invention Grant
- Patent Title: Methods of treating chronic lymphocytic leukemia and small lymphocytic leukemia using a BTK inhibitor
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Application No.: US17370778Application Date: 2021-07-08
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Publication No.: US11771696B2Publication Date: 2023-10-03
- Inventor: Ahmed Hamdy , Wayne Rothbaum , Raquel Izumi , Brian Lannutti , Todd Covey , Roger Ulrich , Dave Johnson , Tjeerd Barf , Allard Kaptein
- Applicant: Acerta Pharma B.V.
- Applicant Address: NL Oss
- Assignee: Acerta Pharma B.V.
- Current Assignee: Acerta Pharma B.V.
- Current Assignee Address: NL Oss
- Agency: Morgan, Lewis & Bockius, LLP
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; A61K39/395 ; A61K45/06 ; C07K16/28

Abstract:
Therapeutic methods of treating chronic lymphocytic leukemia (CLL) and small lymphocytic leukemia (SLL) are described. In certain embodiments, the invention includes therapeutic methods of treating CLL and SLL using a BTK inhibitor. In certain embodiments, the invention includes therapeutic methods of treating subtypes of CLL and SLL using a BTK inhibitor, including subtypes of CLL in patients sensitive to thrombosis and subtypes of CLL that increase monocytes and NK cells in peripheral blood after treatment with a BTK inhibitor. In certain embodiments, the invention includes therapeutic methods of treating CLL and SLL using a combination of a BTK inhibitor and an anti-CD20 antibody.
Public/Granted literature
- US20210401835A1 Methods of Treating Chronic Lymphocytic Leukemia and Small Lymphocytic Leukemia Using a BTK Inhibitor Public/Granted day:2021-12-30
Information query
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