The present invention is directed to a safe and efficient, wearable drug delivery system for delivering one or more drugs directly into a patient's body in a prescribed manner. The wearable drug delivery system includes a drug delivery module including at least one receptor port for receiving and retaining a source of drugs, a skin base attachable to the drug delivery module and containing at least one corresponding drug delivery port for receipt of drugs from the at least one receptor port and a drug-dispensing nozzle for delivering the drug into the patient's system (e.g., into a vein). The drug delivery system additionally includes an electronic control system having a control module and an electronic valve, which may be positioned between the receptor port and the drug delivery port, for control of the flow of the drug in response to input from the control module.