A method for separating a gas mixture flow, n which uses a temperature-change adsorption plant having a number of adsorption units which are operated in a first and a second operating mode. The first operating mode comprises guiding a gas mixture flow at least in part through an adsorption chamber of an adsorption unit and subjecting this flow to an adsorptive exchange with at least one adsorbent. The second operating mode comprises guiding a first heat transfer fluid flow at a first temperature through a heat-exchange arrangement of an adsorption unit. The first operating mode also comprises guiding a second heat transfer fluid flow at a second temperature through the heat-exchange arrangement of the respective adsorption unit. The adsorption units are operated in a third operating mode which comprises guiding a third heat transfer fluid flow at a third temperature through the heat-exchange arrangement of the respective adsorption unit.