Invention Grant
- Patent Title: Compounds and their methods of use
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Application No.: US16885605Application Date: 2020-05-28
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Publication No.: US11773099B2Publication Date: 2023-10-03
- Inventor: Kiran Reddy , Gabriel Martinez Botella , Andrew Mark Griffin , Brian Edward Marron
- Applicant: Praxis Precision Medicines, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Praxis Precision Medicines, Inc.
- Current Assignee: Praxis Precision Medicines, Inc.
- Current Assignee Address: US MA Boston
- Agency: McCarter & English, LLP
- Agent Jonathan M. Sparks
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D471/04
Abstract:
The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. The fused heteroaryl compounds of the disclosure are represented by Formula (I):
wherein X, Y, Z, A, R1 and R2 are as defined in the specification. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including Dravet syndrome or epilepsy are also provided herein.
wherein X, Y, Z, A, R1 and R2 are as defined in the specification. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including Dravet syndrome or epilepsy are also provided herein.
Public/Granted literature
- US20200377506A1 COMPOUNDS AND THEIR METHODS OF USE Public/Granted day:2020-12-03
Information query
