Invention Grant
- Patent Title: Gram-negative lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof in human serum
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Application No.: US17041691Application Date: 2019-03-29
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Publication No.: US11773140B2Publication Date: 2023-10-03
- Inventor: Raymond Schuch
- Applicant: CONTRAFECT CORPORATION
- Applicant Address: US NY Yonkers
- Assignee: CONTRAFECT CORPORATION
- Current Assignee: CONTRAFECT CORPORATION
- Current Assignee Address: US NY Yonkers
- Agency: MH2 TECHNOLOGY LAW GROUP LLP
- International Application: PCT/US2019/024912 2019.03.29
- International Announcement: WO2019/191633A 2019.10.03
- Date entered country: 2020-09-25
- Main IPC: C07K14/005
- IPC: C07K14/005 ; A61P31/04 ; A61K38/16 ; A61K38/17 ; A61K45/06 ; C07K14/47
Abstract:
The present disclosure is directed to lysin-AMP polypeptide constructs, isolated lysin polypeptides, and pharmaceutical compositions comprising the isolated polypeptides and/or lysin-AMP polypeptide constructs. Methods of using the lysin-AMP polypeptide constructs, isolated lysin polypeptides and pharmaceutical compositions are also herein provided. In addition, isolated polynucleotides encoding the lysin-AMP polypeptide constructs and isolated lysin polypeptides are disclosed herein.
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