Invention Grant
- Patent Title: Glucagon-like peptide 1 receptor agonists and uses thereof
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Application No.: US17332215Application Date: 2021-05-27
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Publication No.: US11779633B2Publication Date: 2023-10-10
- Inventor: Yang Wei , Haruka Okamoto , Jesper Gromada , Samuel Davis , Andrew J. Murphy
- Applicant: Regeneran Pharmaceuticals, Inc.
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Fox Rothschild LLP
- Agent Thomas Triolo
- The original application number of the division: US16137662 2018.09.21
- Main IPC: A61K38/26
- IPC: A61K38/26 ; C07K16/28 ; C07K14/605 ; A61P3/04 ; A61P3/10 ; A61K31/155 ; A61K31/5415 ; C07K16/08 ; C12N15/62 ; A61K38/00

Abstract:
The present invention provides modified glucagon-like peptide 1 (GLP1) polypeptides, fusion proteins comprising modified GLP1 polypeptides, and methods of use thereof. In various embodiments of the invention, the fusion proteins are GLP1 receptor agonists that comprise a modified GLP1 fused to a stabilizing domain. In some embodiments, the fusion proteins comprising modified GLP1 are useful for treating or ameliorating a symptom or indication of a disorder such as obesity and diabetes.
Public/Granted literature
- US20210283225A1 GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS AND USES THEREOF Public/Granted day:2021-09-16
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