- Patent Title: Fc binding proteins with cysteine in the C-terminal helical region
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Application No.: US16637323Application Date: 2018-08-06
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Publication No.: US11779860B2Publication Date: 2023-10-10
- Inventor: Erik Fiedler , Ulrich Haupts
- Applicant: Repligen Corporation
- Applicant Address: US MA Waltham
- Assignee: Repligen Corporation
- Current Assignee: Repligen Corporation
- Current Assignee Address: US MA Waltham
- Agency: KDW Firm PLLC
- Priority: WO TEP2017069976 2017.08.07 EP 154731 2018.02.01 EP 163964 2018.03.26
- International Application: PCT/EP2018/071232 2018.08.06
- International Announcement: WO2019/030156A 2019.02.14
- Date entered country: 2020-02-07
- Main IPC: B01D15/38
- IPC: B01D15/38 ; B01J20/32 ; C07K1/22 ; C07K14/31
Abstract:
The present invention relates to Fc binding proteins comprising one or more domains with Cysteine in the C-terminal helical region. The invention further relates to affinity matrices comprising the Fc binding proteins of the invention. The invention also relates to a use of these Fc binding proteins or affinity matrices for affinity purification of immunoglobulins and to methods of affinity purification using the Fc binding proteins of the invention.
Public/Granted literature
- US20200238197A1 FC BINDING PROTEINS WITH CYSTEINE IN THE C-TERMINAL HELICAL REGION Public/Granted day:2020-07-30
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