A device for operating a power seat of a vehicle, the device being able to show exact operation directions of a power seat by operation of switches to a user, and enabling the user to recognize the exact selection state and operation direction of desired switches so that the user can more conveniently use the switches by displaying one arrow showing the operation direction of the seat when each of a plurality of touch sensors, which is disposed in each of the switches of a switch module for operating the seat to show operation direction of the seat, senses a touch.