Methods and systems for efficiently loading cargo transports, such as cargo aircraft, are described. The methods and systems rely upon payload profiles for various payloads where the payloads include repeatable payloads that have the same characteristics. Based on the payload profile, the payload is positioned at a designated location in an interior cargo bay of the cargo transport. The designated location is denoted by one or more pre-formed markings in the interior cargo bay that establish where a payload having the respective payload profile should be positioned in the bay. The payload can then be secured in the bay. Because the designated location accounts for centers of gravity, the payload can be loaded and secured in the bay without having to run various calculations each time a payload is loaded. Systems and methods related to how the payloads are packaged in an efficient, expeditious manner are also provided.