Invention Grant
- Patent Title: Modified viral vectors and methods of making and using the same
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Application No.: US16911171Application Date: 2020-06-24
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Publication No.: US11780886B2Publication Date: 2023-10-10
- Inventor: David Johannes Francois Du Plessis
- Applicant: uniQure IP B.V.
- Applicant Address: NL Amsterdam
- Assignee: uniQure IP B.V.
- Current Assignee: uniQure IP B.V.
- Current Assignee Address: NL Amsterdam
- Agency: FOLEY & LARDNER LLP
- Agent Sunit Talapatra
- Priority: EP 211221 2017.12.29
- Main IPC: C07K14/005
- IPC: C07K14/005 ; A61K35/76 ; C12N7/00 ; C12N15/86

Abstract:
The present invention relates to production of parvoviral vectors to produce adeno-associated virus (AAV) for gene therapy. In particular the invention relates to improvements in parvoviral vectors that increase the packaging capacity, production efficiency, and infectivity of AAV virions that is necessary for large scale manufacturing of AAV for clinical purposes.
Public/Granted literature
- US20200325181A1 MODIFIED VIRAL VECTORS AND METHODS OF MAKING AND USING THE SAME Public/Granted day:2020-10-15
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