Invention Grant
- Patent Title: CD47 targeted therapies for the treatment of infectious disease
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Application No.: US17550881Application Date: 2021-12-14
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Publication No.: US11780931B2Publication Date: 2023-10-10
- Inventor: Kipp Andrew Weiskopf , Kim J. Hasenkrug , Cheryl A. Stoddart , Joseph McCrary McCune , Irving L. Weissman
- Applicant: The Board of Trustees of the Leland Stanford Junior University , The United States of America, as represented by the Secretary, Department of Health and Human Services , The Regents of the University of California
- Applicant Address: US CA Stanford
- Assignee: The Board of Trustees of the Leland Stanford Junior University,The United States of America, as represented by the Secretary, Department of Health and Human Services,The Regents of the University of California
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University,The United States of America, as represented by the Secretary, Department of Health and Human Services,The Regents of the University of California
- Current Assignee Address: US CA Stanford; US MD Bethesda; US CA Oakland
- Agency: Bozicevic, Field & Francis LLP
- Agent Pamela J. Sherwood
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K38/17 ; A61K39/00
Abstract:
Methods are provided for treating a subject with for an intracellular pathogen infection, by administering an agent that reduces the binding of CD47 on a infected cell to SIRPα on a host phagocytic cell, in an effective dose for increasing the phagocytosis of infected cells.
Public/Granted literature
- US20220098322A1 CD47 TARGETED THERAPIES FOR THE TREATMENT OF INFECTIOUS DISEASE Public/Granted day:2022-03-31
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