Invention Grant
- Patent Title: Reducing the accumulation of imines/enamines for the production of amino acids or amino acid-derived products
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Application No.: US16768336Application Date: 2017-11-29
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Publication No.: US11781163B2Publication Date: 2023-10-10
- Inventor: Howard Chou , Ling Chen , Xiucai Liu
- Applicant: CATHAY BIOTECH INC. , CIBT AMERICA INC.
- Applicant Address: CN DE Shanghai
- Assignee: CATHAY BIOTECH INC.,CIBT AMERICA INC.
- Current Assignee: CATHAY BIOTECH INC.,CIBT AMERICA INC.
- Current Assignee Address: CN Shanghai; US DE Newark
- Agency: ROTHWELL, FIGG, ERNST & MANBECK, P.C.
- International Application: PCT/CN2017/113505 2017.11.29
- International Announcement: WO2019/104518A 2019.06.06
- Date entered country: 2020-05-29
- Main IPC: C12P13/08
- IPC: C12P13/08 ; C12N9/12 ; C12N9/78 ; C12N9/88 ; C12P13/00
Abstract:
Provided microorganisms genetically modified to overexpress an imine/enamine deaminase to enhance the production of lysine and lysine derivatives by the microorganism. Also provided a method of generating such microorganism, and methods of producing lysine and lysine derivatives using the genetically modified microorganisms.
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