Invention Grant
- Patent Title: Modified biotin-binding proteins for immobilization
-
Application No.: US16841450Application Date: 2020-04-06
-
Publication No.: US11781177B2Publication Date: 2023-10-10
- Inventor: Satwik Kamtekar , Lubomir Sebo , Leewin Chern , Thomas Linsky , Jeremiah Hanes , Erik Miller , Ying Yang , Stephen Yue
- Applicant: Pacific Biosciences of California, Inc.
- Applicant Address: US CA Menlo Park
- Assignee: Pacific Biosciences of California, Inc.
- Current Assignee: Pacific Biosciences of California, Inc.
- Current Assignee Address: US CA Menlo Park
- Agent Monicia Elrod-Erickson
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C12Q1/6848 ; C12N9/22 ; C07K14/36
Abstract:
Compositions comprising covalently modified and mutated biotin-binding proteins, particularly biotin-binding proteins having a negative charge at physiological pH, are provided. Methods of producing such proteins are also provided, as are methods of immobilizing, sequencing, and making nucleic acids employing such proteins.
Information query
