A method and a system for switching from grid-connected to grid-disconnected, and a power conversion system are provided. The method includes determining whether a power grid is abnormal based on a power grid parameter obtained when a PCS is grid-connected and operates in a current source mode, turning off a switching cabinet if the power grid is abnormal, switching from a current source mode to a voltage source mode, sending a command to instruct a grid-connected/grid-disconnected switch to switch from a grid-connected loop to a grid-disconnected loop, controlling an output parameter to smoothly transit from an abnormal parameter value recorded when the power grid is abnormal to a rated parameter value, and supplying power to a load according to the rated parameter value. In this way, seamless switching from grid-connected to grid-disconnected can be achieved, thereby ensuring stability of power supply.