Embodiments include methods for a network node configured to communicate with wireless devices via orthogonal frequency division multiple access (OFDMA) signaling and non-OFDMA signaling. Such methods include creating a frequency gap in the OFDMA signaling, with the frequency gap including one or more adjacent OFDM sub-carriers. Such methods include selecting a center frequency for the non-OFDMA signaling to be within the frequency gap and selecting one or more modulation and coding schemes (MCS) for the OFDMA signaling based on interference to the OFDMA signaling by the non-OFDMA signaling. Other embodiments include network nodes configured to perform such methods, and computer-readable media storing computer-executable instructions that embody such methods.