A method and a device for transmitting/receiving a signal in a wireless communication system, according to one embodiment of the present invention, perform a two-step or four-step random access procedure, and monitor a PDCCH according to a DRX configuration, wherein the PRACH transmitted in the random access procedure is transmitted on a specific RO from among a plurality of ROs, and a starting RB index of the specific RO can be determined on the basis of (i) the lowest RB index of an RB set including the specific RO, (ii) the starting RB index of an RO positioned at the lowest frequency, and (iii) the lowest RB index of an RB set including the RO positioned at the lowest frequency.