Invention Grant
- Patent Title: Human plasma kallikrein inhibitors
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Application No.: US17374335Application Date: 2021-07-13
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Publication No.: US11807605B2Publication Date: 2023-11-07
- Inventor: Pravin L. Kotian , Yarlagadda S. Babu , V. Satish Kumar , Weihe Zhang , Lakshminarayana Vogeti
- Applicant: BioCryst Pharmaceuticals, Inc.
- Applicant Address: US NC Durham
- Assignee: BioCryst Pharmaceuticals, Inc.
- Current Assignee: BioCryst Pharmaceuticals, Inc.
- Current Assignee Address: US NC Durham
- Agency: Foley Hoag LLP
- Agent Dana M. Gordon; Laura A. Wzorek
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/444 ; C07D207/16 ; C07D401/12 ; C07D409/14 ; C07D207/24 ; A61P7/00 ; A61P17/10 ; A61P17/00

Abstract:
Disclosed are compounds of formula I, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of plasma kallikrein. Also provided are pharmaceutical compositions comprising at least one compound of the invention, and methods involving use of the compounds and compositions of the invention in the treatment and prevention of diseases and conditions characterized by unwanted plasma kallikrein activity.
Public/Granted literature
- US20220098151A1 HUMAN PLASMA KALLIKREIN INHIBITORS Public/Granted day:2022-03-31
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