A method for execution by an input/output (IO) control module of an integrated circuit (IC) includes determining whether a programmable IO interface module is for dynamic or static use. The programmable IO interface module includes a configurable front-end module and a configurable back-end module. When the programmable IO interface module is for the dynamic use, determining to configure the programmable IO interface module as the dynamic use of a configuration of a plurality of configurations. The plurality of configurations includes a bidirectional interface, an input, an output, a concurrent drive and sense interface, and a concurrent transmit-receive interface. The method further includes configuring the front-end module in accordance with the configuration, configuring the back-end module in accordance with the configuration, and determining whether to change the configuration to another configuration of the plurality of configurations.