Provided are a color generation system, method and apparatus of a to-be-displayed object, a display device and a medium. The color generation system of a to-be-displayed object includes a to-be-displayed object processing module, a color setting module and a color generation module. The to-be-displayed object processing module is configured to preprocess a sampled to-be-displayed object, and determine to-be-displayed object information of the sampled to-be-displayed object according to the preprocessed sampled to-be-displayed object. The color setting module is configured to generate a to-be-displayed object color mapping table based on the to-be-displayed object information, and parse the to-be-displayed object information and color information in the to-be-displayed object color mapping table to obtain a subpixel information component of a display interface. The color generation module is configured to configure a display color of the sampled to-be-displayed object on the display interface according to the subpixel information component of the display interface.