Invention Grant
- Patent Title: JAK1 pathway inhibitors for the treatment of cytokine-related disorders
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Application No.: US17379336Application Date: 2021-07-19
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Publication No.: US11833152B2Publication Date: 2023-12-05
- Inventor: Michael O'Neill Montgomery , Ahmad Naim , Susan Snodgrass
- Applicant: Incyte Corporation
- Applicant Address: US DE Wilmington
- Assignee: Incyte Corporation
- Current Assignee: Incyte Corporation
- Current Assignee Address: US DE Wilmington
- Agency: Fish & Richardson P.C.
- Main IPC: A61K31/397
- IPC: A61K31/397 ; A61K31/4427 ; A61K31/56 ; A61K31/519 ; A61P37/02 ; A61K31/4155 ; A61K31/573 ; C07K16/28 ; A61K31/437 ; A61P37/00

Abstract:
This disclosure relates to JAK1 pathway inhibitors and the use thereof in treating cytokine-related diseases or disorders such as cytokine release syndrome (CRS), hemophagocytic lymphohistiocytosis (HLH), macrophage activation syndrome (MAS), and CAR-T-cell-related encephalopathy syndrome (CRES).
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