A method of adapting a Lab setpoint color value of multicolored printed products, wherein a special color is replaced by process colors using an ICC color profile. A measurement point that is assigned to the replaced special color on the printed product is metrologically acquired using a color measuring system and a Lab actual color value of the measurement point is calculated. The ICC color profile or a standardized ICC color profile is used for computing the color composition of the Lab setpoint color value from the participating process colors. Changes of the layer thicknesses of the participating process colors are ascertained to achieve a predetermined Lab setpoint color value of the measurement point using a digital tool or a digital model. The participating process colors are adapted using the ascertained changes of their layer thicknesses.