A pre-chamber spark plug for a combustion chamber of an internal combustion engine includes a pre-chamber which has a plurality of openings. A fuel-air mixture is introducible from the combustion chamber into the pre-chamber via the plurality of openings. With respect to an imaginary plane running in a longitudinal extension direction of the pre-chamber and dividing the pre-chamber into a first half and a second half of equal size, first openings are disposed in the first half and second openings are disposed in the second half. The first openings enclose a respective first angle with the imaginary plane, the second openings enclose a respective second angle with the imaginary plane, and a mean value of the first angles is greater than a mean value of the second angles. The plurality of openings are configured rotationally asymmetrically about an imaginary axis running on the imaginary plane.