Invention Grant
- Patent Title: Inhibition of dipeptide repeat proteins
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Application No.: US17584522Application Date: 2022-01-26
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Publication No.: US11857534B2Publication Date: 2024-01-02
- Inventor: Fernando G. Vieira , Alan Premasiri , Anna Gill
- Applicant: ALS Therapy Development Institute
- Applicant Address: US MA Cambridge
- Assignee: ALS Therapy Development Institute
- Current Assignee: ALS Therapy Development Institute
- Current Assignee Address: US MA Cambridge
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jeanne M. DiGiorgio
- The original application number of the division: US16895875 2020.06.08
- Main IPC: A61K31/40
- IPC: A61K31/40 ; A61K31/4155 ; A61K31/4545 ; A61K31/428 ; A61K45/06
Abstract:
Methods are disclosed for treating neurodegenerative disorders, such as ALS and FTD by using an effective amount of a type I protein arginine methyltransferase (Type I PRMT) inhibitor to decrease cellular toxicity caused by dipeptide repeat proteins (DRPs).
Public/Granted literature
- US20220142974A1 INHIBITION OF DIPEPTIDE REPEAT PROTEINS Public/Granted day:2022-05-12
Information query
