Invention Grant
- Patent Title: Combination therapies for treatment of laminopathies, cellular aging, and atherosclerosis
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Application No.: US16916145Application Date: 2020-06-30
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Publication No.: US11857541B2Publication Date: 2024-01-02
- Inventor: Leslie B. Gordon , Mark W. Kieran , Monica E. Kleinman
- Applicant: Leslie B. Gordon , Mark W. Kieran , Monica E. Kleinman
- Applicant Address: US MA Foxboro
- Assignee: Leslie B. Gordon,Mark W. Kieran,Monica E. Kleinman
- Current Assignee: Leslie B. Gordon,Mark W. Kieran,Monica E. Kleinman
- Current Assignee Address: US MA Foxboro
- Agency: JMB Davis Ben-David
- The original application number of the division: US16159716 2018.10.15
- Main IPC: A61K31/436
- IPC: A61K31/436 ; A61K31/4545 ; A61K9/00 ; A61K9/20 ; A61K45/06 ; A61K31/22 ; A61K31/675 ; A61K31/55 ; A61K31/663
Abstract:
Provided herein are combination therapies for the treatment of progeroid diseases and conditions, cellular aging, bone diseases, and cardiovascular diseases. The provided combination therapies target the aberrant farnesylation of the mutant lamin A protein progerin and increase progerin clearance.
Public/Granted literature
- US20200330443A1 COMBINATION THERAPIES FOR TREATMENT OF LAMINOPATHIES, CELLULAR AGING, AND ATHEROSCLEROSIS Public/Granted day:2020-10-22
Information query
IPC分类:
