Invention Grant
- Patent Title: Benzathine analogs
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Application No.: US16953201Application Date: 2020-11-19
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Publication No.: US11857550B2Publication Date: 2024-01-02
- Inventor: Beibei Chen , Rama K. Mallampalli
- Applicant: University of Pittsburgh—Of the Commonwealth System of Higher Education , The United States Government as represented by the Department of Veterans Affairs
- Applicant Address: US PA Pittsburgh
- Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education,The United States Government as Represented By the Department of Veterans Affairs
- Current Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education,The United States Government as Represented By the Department of Veterans Affairs
- Current Assignee Address: US PA Pittsburgh; US DC Washington
- Agency: Klarquist Sparkman, LLP
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/137 ; C07D239/26 ; C07D403/12 ; A61P3/10 ; A61P11/06 ; A61P19/00 ; A61P25/00 ; A61P35/00 ; C07D231/12 ; C07D233/61 ; A61K31/341 ; A61K31/381 ; A61K31/402 ; A61K31/4155 ; A61K31/427 ; A61K31/4418 ; A61K31/5375 ; C07D213/36 ; C07C211/01 ; C07C211/53 ; C07C229/38 ; C07D207/06 ; C07D211/14 ; C07D213/06 ; C07D213/38 ; C07D265/30 ; C07D277/28 ; A61K31/4178 ; A61K31/435 ; A61K31/444 ; C07D233/64 ; C07D401/12 ; C07D295/135

Abstract:
A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of:
wherein X is a divalent linking moiety; and
R1-R10 are each individually H, optionally-substituted alkyl, optionally-substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, halogen, amino, or hydroxy, provided that at least one of R3 or R8 is an optionally-substituted alkyl, a substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, or halogen.
wherein X is a divalent linking moiety; and
R1-R10 are each individually H, optionally-substituted alkyl, optionally-substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, halogen, amino, or hydroxy, provided that at least one of R3 or R8 is an optionally-substituted alkyl, a substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, or halogen.
Public/Granted literature
- US20210315895A1 BENZATHINE ANALOGS Public/Granted day:2021-10-14
Information query
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